PRACTICAL AE MANAGEMENT WITH TRODELVY1
Management of diarrhoea
Patients who exhibit an excessive cholinergic response to treatment with TRODELVY (e.g. abdominal cramping, diarrhoea, salivation, etc.) can receive appropriate treatment (e.g. atropine) for subsequent treatments with TRODELVY.1
IN THE ASCENT TRIAL TRODELVY GROUP,MOST INSTANCES OF DIARRHOEA OCCURRED WITHIN THE FIRST 2 CYCLES AND LASTED ABOUT 1 WEEK3
ABBREVIATIONS:
AE, adverse event.
REFERENCES:
1. TRODELVY (sacituzumab govitecan) Summary of Product Characteristics, June 2025. 2. Bardia A, et al. N Engl J Med. 2021;384(16):1529–1541. 3. Rugo H, et al. NPJ Breast Cancer. 2022; 8: 98.doi: 10.1038/s41523-022-00467-1.