Practical AE management with TRODELVY1
Management of neutropenia
In the ASCENT trial TRODELVY group, Most instances of neutropenia occurred within the first 2 cycles and lasted about 1 week3
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0%Treatment discontinuation due to neutropenia or febrile neutropenia
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46%Treatment interruption due to neutropenia or febrile neutropenia
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11%Dose reduction due to neutropenia or febrile neutropenia
All events of Grade 3-4 neutropenia in patients treated with
TRODELVY were resolved
ABBREVIATIONS:
AE, adverse event; G-CSF, granulocyte-colony stimulating factor.
REFERENCES:
- TRODELVY (sacituzumab govitecan) Summary of Product Characteristics, July 2023.
- Bardia A, et al. N Engl J Med. 2021;384(16):1529–1541.
- Rugo H, et al. NPJ Breast Cancer. 2022; 8: 98.doi: 10.1038/s41523-022-00467-1.